Last updated August 21, 2026 How Long Do Edibles Last? In controlled oral-cannabis research, noticeable THC effects lasted about 6 to 8 hours, but public-health guidance warns that the experience can last up to 12 hours. Some people may notice fatigue, slowed thinking, or other residual effects for as long as 24 hours, especially after a large amount of THC. The timeline is not exact. THC amount, product formulation, food, ind… Read more